Zhengliang Ma Selected Research

N-Methyl-D-Aspartate Receptors (NMDA Receptors)

11/2016	Activated Glia Increased the Level of Proinflammatory Cytokines in a Resiniferatoxin-Induced Neuropathic Pain Rat Model.
3/2016	The effects of an intraperitoneal single low dose of ketamine in attenuating the postoperative skin/muscle incision and retraction-induced pain related to the inhibition of N-methyl-D-aspartate receptors in the spinal cord.
2/2016	Regulation of the NR2B-CREB-CRTC1 Signaling Pathway Contributes to Circadian Pain in Murine Model of Chronic Constriction Injury.
1/2016	Activation of spinal MrgC-Gi-NR2B-nNOS signaling pathway by Mas oncogene-related gene C receptor agonist bovine adrenal medulla 8-22 attenuates bone cancer pain in mice.
3/2015	Kinesin superfamily protein 17 contributes to the development of bone cancer pain by participating in NR2B transport in the spinal cord of mice.
9/2014	Cdk5 inhibitor roscovitine alleviates neuropathic pain in the dorsal root ganglia by downregulating N-methyl-D-aspartate receptor subunit 2A.
9/2014	The inhibitor of calcium/calmodulin-dependent protein kinase II KN93 attenuates bone cancer pain via inhibition of KIF17/NR2B trafficking in mice.
7/2014	The effect of intrathecal administration TRPA1 antagonists in a rat model of neuropathic pain.
7/2014	Intrathecal administration of roscovitine prevents remifentanil-induced postoperative hyperalgesia and decreases the phosphorylation of N-methyl-D-aspartate receptor and metabotropic glutamate receptor 5 in spinal cord.
6/2014	Activation of GRs-Akt-nNOs-NR2B signaling pathway by second dose GR agonist contributes to exacerbated hyperalgesia in a rat model of radicular pain.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Zhengliang Ma Research Topics

Disease

57	Pain (Aches) 03/2024 - 12/2009
43	Hyperalgesia 05/2024 - 12/2009
23	Postoperative Pain 02/2024 - 12/2009
19	Bone Neoplasms (Bone Cancer) 01/2023 - 10/2010
17	Neuralgia (Stump Neuralgia) 03/2024 - 10/2010
13	Cognitive Dysfunction 03/2024 - 01/2012
10	Chronic Pain 10/2023 - 07/2014
8	Neoplasms (Cancer) 01/2024 - 10/2010
7	Postoperative Cognitive Complications 01/2023 - 01/2012
7	Inflammation (Inflammations) 04/2020 - 07/2012
6	Neuroinflammatory Diseases 05/2024 - 01/2012
4	Mitochondrial Diseases (Mitochondrial Disease) 03/2024 - 10/2021
4	Hypersensitivity (Allergy) 10/2020 - 01/2017
4	Spinal Cord Injuries (Spinal Cord Injury) 01/2018 - 04/2014
4	Surgical Wound 03/2017 - 09/2014
3	Neuroblastoma 03/2024 - 01/2021
3	Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder) 01/2022 - 01/2016
3	Kyphosis 12/2018 - 02/2013
3	Ankylosing Spondylitis 12/2018 - 02/2013
3	Peripheral Nerve Injuries 01/2018 - 07/2013
3	Osteosarcoma (Osteogenic Sarcoma) 01/2018 - 07/2012
3	Cancer Pain 09/2014 - 07/2012
2	Emergence Delirium 03/2024 - 01/2022
2	Neurocognitive Disorders (Clerambault Syndrome) 03/2024 - 12/2022
2	Cough 10/2023 - 01/2023
2	Sepsis (Septicemia) 08/2023 - 10/2021
2	Inguinal Hernia (Direct Inguinal Hernia) 01/2023 - 01/2020
2	Sleep Deprivation 01/2023 - 01/2023
2	Delirium 08/2022 - 01/2022
2	Acute Pain 01/2022 - 01/2020
2	Ischemia 10/2021 - 01/2012
2	Type 2 Diabetes Mellitus (MODY) 01/2021 - 01/2020
2	Hyperglycemia 01/2021 - 01/2020
2	Insulin Resistance 01/2021 - 01/2020
2	Memory Disorders (Memory Loss) 01/2020 - 01/2018

Drug/Important Bio-Agent (IBA)

16	Proteins (Proteins, Gene)FDA Link 03/2024 - 01/2012
14	Analgesics (Analgesic Drugs)IBA 01/2023 - 11/2013
14	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 11/2016 - 12/2009
12	Remifentanil (Ultiva)FDA Link 11/2023 - 12/2009
12	Isoflurane FDA LinkGeneric 11/2023 - 03/2016
12	CytokinesIBA 01/2023 - 04/2014
10	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2021 - 10/2010
9	Interleukin-6 (Interleukin 6)IBA 01/2024 - 01/2012
7	Messenger RNA (mRNA)IBA 11/2023 - 01/2012
7	salicylhydroxamic acid (SHAM)IBA 11/2018 - 10/2010
5	InterleukinsIBA 01/2020 - 04/2014
4	Anesthetics (Anesthetic Agents)IBA 10/2023 - 01/2015
4	Dexmedetomidine FDA Link 01/2023 - 08/2017
4	Opioid Analgesics (Opioids)IBA 01/2023 - 12/2009
4	Antisense OligonucleotidesIBA 11/2020 - 07/2013
4	Cannabinoid Receptors (Cannabinoid Receptor)IBA 10/2020 - 04/2014
4	Phosphotransferases (Kinase)IBA 01/2020 - 07/2014
4	Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA 02/2019 - 09/2014
4	N-Methylaspartate (NMDA)IBA 01/2019 - 12/2009
4	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2018 - 12/2014
4	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA 08/2017 - 01/2015
3	Biomarkers (Surrogate Marker)IBA 03/2024 - 04/2015
3	EsketamineIBA 01/2024 - 01/2022
3	Minocycline (Cyclops)FDA LinkGeneric 01/2024 - 01/2016
3	EnzymesIBA 12/2020 - 04/2014
3	Dexamethasone (Maxidex)FDA LinkGeneric 03/2020 - 06/2011
3	Ketamine FDA LinkGeneric 01/2020 - 12/2009
3	1- (5- chloro- 2,4- dimethoxyphenyl)- 3- (5- methylisoxazol- 3- yl)ureaIBA 01/2019 - 01/2015
3	Mifepristone (RU 486)FDA Link 01/2019 - 06/2011
3	Spironolactone (Aldactone)FDA LinkGeneric 01/2019 - 06/2011
3	N- (1- azabicyclo(2.2.2)oct- 3- yl)furo(2,3- c)pyridine- 5- carboxamideIBA 01/2019 - 01/2015
3	Cyclic AMP Response Element-Binding Protein (Cyclic AMP-Responsive DNA-Binding Protein)IBA 01/2017 - 07/2013
3	RoscovitineIBA 09/2014 - 07/2012
3	NR2B NMDA receptorIBA 11/2013 - 12/2009
2	Glucose (Dextrose)FDA LinkGeneric 05/2024 - 01/2021
2	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2024 - 01/2015
2	Hematoxylin (Haematoxylon)IBA 01/2024 - 04/2020
2	Eosine Yellowish-(YS) (Eosin)IBA 01/2024 - 04/2020
2	Tight Junction ProteinsIBA 11/2023 - 04/2020
2	Ropivacaine (Naropin)FDA LinkGeneric 10/2023 - 01/2023
2	Fatty Acids (Saturated Fatty Acids)IBA 01/2023 - 06/2017
2	Transcription Factors (Transcription Factor)IBA 01/2023 - 01/2018
2	dehydrocorydalinIBA 01/2023 - 01/2018
2	Connexin 43 (Connexin43)IBA 12/2022 - 03/2022
2	General AnestheticsIBA 03/2022 - 01/2021
2	Insulin (Novolin)FDA Link 01/2021 - 01/2020
2	Fentanyl (Sublimaze)FDA LinkGeneric 11/2020 - 03/2020
2	Pioglitazone (Actos)FDA Link 11/2020 - 04/2020
2	GTP-Binding Proteins (G-Protein)IBA 07/2020 - 01/2020
2	Estrogen ReceptorsIBA 07/2020 - 01/2020
2	Cysteine (L-Cysteine)FDA Link 07/2020 - 03/2017
2	Matrix Metalloproteinase 9 (Gelatinase B)IBA 07/2020 - 03/2017
2	GlucocorticoidsIBA 01/2019 - 01/2017

Therapy/Procedure

18	Spinal Injections 03/2024 - 01/2012
16	Anesthesia 03/2024 - 03/2016
12	Therapeutics 03/2022 - 10/2010
6	Intraperitoneal Injections 01/2024 - 10/2010
5	Analgesia 01/2023 - 11/2013
3	Osteotomy 12/2018 - 02/2013
3	General Anesthesia 01/2016 - 01/2015
2	Hip Replacement Arthroplasty (Total Hip Replacement) 04/2024 - 01/2023
2	Knee Replacement Arthroplasty (Total Knee Replacement) 02/2024 - 01/2023
2	Arthroplasty 03/2023 - 01/2023
2	Perioperative Period 01/2023 - 01/2019
2	Length of Stay 08/2022 - 03/2020